CURRICULUM VITAE

Date of Preparation: March 25, 2005

YI-HONG ZHANG, M.D., Ph.D.


TITLE    Research Assistant Professor

ADDRESS 

Department of Anatomy and Neurobiology
University of Tennessee Health Science Center
855 Monroe Ave., Suite 515
Memphis, TN 38163
Tel. (901) 448-1223
Fax: (901) 448-7193
Email: yzhang32@utmem.edu

EDUCATION

M.D.: Capital Institute of Medicine, Beijing, China (1991)

Ph.D.: Department of Physiology, Osaka University Medical School, Osaka, Japan (1997)

Postdoctoral training: Harvard Medical School (laboratory of Dr. Clifford B. Saper, Beth Israel Deaconess Medical Center, 1997 - 1999); University of Calgary (laboratory of Dr. Quentin J. Pittman, 1999 - 2001)

FIELD OF RESEARCH INTEREST

Neuroanatomy and neurophysiology/neuropharmacology in pain system, inflammation, fever, and thermoregulation system.

PROFESSIONAL EXPERIENCE

2003 - Present    Research Assistant Professor, Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, Tennessee.

2002 - 2003    Scientist, Pre-clinical Research Group, Bioaxone Therapeutique Inc., Montreal, Quebec, Canada.

2001 - 2002    Research associate, Neuroscience Program affiliated with Department of Cellular and Molecular Medicine, Ottawa Health Research Institute (OHRI) and University of Ottawa, Ottawa, Ontario, Canada.

1999 - 2001    Postdoctoral fellow, Department of Physiology and Biophysics, University of Calgary, Calgary, Alberta, Canada.

1997 - 1999    Postdoctoral fellow, Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.

ORGANIZATIONAL MEMBERSHIPS

·    Society for Neuroscience
·    American Pain Society

HONORS, AWARDS

1999 - 2001    Heart and Stroke Foundation of Canada Fellowship
1997    Yasu Kuno Memorial Award of Physiological Society of Japan
1997    Ph.D. in Physiology, Osaka University Medical School, Osaka, Japan
1991    M.D. in Clinic Medicine, Capital Institute of Medicine, Beijing, China

LANGUAGES

Fluent English, Japanese, and Chinese (mother tongue)

PUBLICATIONS

1.    Storbeck CJ, Daniel K, Zhang Y-H, Lunde J, Scime A, Asakura A, Jasmin B, Korneluk RG, and Sabourin LA. Ste20-like kinase SLK displays myofiber type specificity and is involved in C2C12 myoblast differentiation. Muscle Nerve. 2004, 29 (4): 553-64

2.    Zhang Y-H, Lu J, Elmquist JK, and Saper CB. Specific roles of cyclooxygenase-1 and cyclooxygenase-2 in lipopolysaccharide induced fever and Fos expression in rat brain.
J Comp Neurol. 2003, 463: 3–12

3.    Zhang Y-H, Hume K, Cadonic R, Thompson CS, Hakim AM, Staines W, and Sabourin LA. Characterization of Sterile20-like kinase (SLK) expression in the central nervous system (CNS) and animal model of stroke. Dev Brain Res. 2002, 139: 205-215

4.    Lu J, Zhang Y-H, Chou T, Gaus SE, Elmquist JK, Shiromani P, and Saper CB. Contrasting effects of ibotenate lesions of the paraventricular nucleus and subparaventricular zone on sleep-wake cycle and temperature regulation. J Neurosci. 2001, 21 (13): 4864-4874

5.    Zhang Y-H, Lu J, Elmquist JK, and Saper CB. Lipopolysaccharide activates specific populations of hypothalamic and brainstem neurons that project to the spinal cord.
J Neurosci.  2000, 20 (17): 6578-6586

6.    Kazuyuki K, Hosono T, Zhang Y-H, and Chen X-M. Neuronal networks controlling thermoregulatory effectors. Prog Brain Res. 1998, 115: 49-62

7.    Zhang Y-H, Hosono T, Yanase-Fujiwara M, Chen X-M, and Kanosue K. Effect of midbrain stimulations on thermoregulatory vasomotor responses in rats. J Physiol. 1997, 503 ( Pt 1): 177-86

8.    Hosono T, Yanase-Fujiwara M, Zhang Y-H, Chen X-M, Fukuda Y, Asaki Y, Yamaji K, and Kanosue K. Effect of gonadotropin releasing hormone on thermoregulatory vasomotor activity in ovariectomized female rats. Brain Res. 1997, 754 (1-2): 88-94

9.    Hosono T, Chen X-M, Zhang Y-H, and Kanosue K. Effects of estrogen on thermoregulatory responses in freely moving female rats. Ann N Y Acad Sci. 1997, 813: 207-10

10.    Zhang Y-H, Yamada K, Hosono T, Chen X-M, Shiosaka S, and Kanosue K. Efferent neuronal organization of thermoregulatory vasomotor control. Ann N Y Acad Sci. 1997, 813: 117-22

11.    Zhang Y-H, Yanase-Fujiwara M, Hosono T, and Kanosue K. Warm and cold signals from the preoptic area: which contribute more to the control of shivering in rats? J Physiol. 1995, 485 ( Pt 1): 195-202

12.    Kanosue K, Zhang Y-H, Yanase-Fujiwara M, and Hosono T. Hypothalamic network for thermoregulatory shivering. Am J Physiol. 1994, 267 (1 Pt 2): R275-82

ABSTRACTS

1.    Zhang Y-H, Thompson CS, Cadonic R, Hume K, Hakim AM, and Sabourin LA. Characterization of Sterile20-like kinase (SLK) expression in the central nervous system (CNS) and animal model of stroke. OHRI. Ann. Cele. Res. Symposium. Abstr. 2002

2.    Zhang Y-H, Elmquist JK, and Saper CB. Intraperitoneal cyclooxygenase-2 (COX-2) inhibitor affects lipopolysaccharide (LPS)-induced fever and Fos expression in rat brain. Soc. Neurosci. Abstr. 1999, 25: 1695

3.    Chou T, Lu J, Zhang Y-H, Gaus SE, Elmquist JK, Shiromani P, and Saper CB. Distinct lesions of the subparaventricular zone (SPZ) affect circadian rhythm of sleep vs. temperature. Soc. Neurosci. Abstr. 1999, 25: 1370

4.    Zhang Y-H, Elmquist JK, and Saper CB. Intravenous lipopolysaccharide activates neurons in the paraventricular nucleus of hypothalamus projecting to the spinal cord. Soc. Neurosci. Abstr. 1998, 24: 367

5.    Zhang Y-H, Yamada K, Yanase-Fujiwara M, Hosono T, Chen XM, and Kanosue K. Projections from the preoptic area to the midbrain for thermoregulatory vasomotor control in rats. Soc. Neurosci. Abstr. 1995, 21: 880

6.    Zhang, Y-H, Yamada K, Yanase-Fujiwara M, Hosono T, Chen X-M, and Kanosue K. Projections from the preoptic area to the midbrain for thermoregulatory vasomotor control in rats.  Japan Neurosci. Soc. Abstr. 1994

7.    Zhang, Y-H, Yanase-Fujiwara M, Hosono T, Yamada K, and Kanosue K. Preoptic warm-sensitive neurons contribute more to the control of shivering than cold-sensitive neurons. Physiol. Soc. Japan Abstr. 1994


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